Psychoneuroimmunology (PNI) - the interactions among the mind, nervous system, and immune system - is a new discipline that has emerged only in the last fifty years. Even more recent but no less important have been the many advances in and applications of psychology to PNI, the contributions of which are essential to the vitality of the rapidly growing field. The Oxford Handbook of Psychoneuroimmunology comprises perspectives on the state-of-the-art applications of psychological theory to PNI. Chapters in the volume represent the entire range of levels of analysis in psychoneuroimmunology. Genes within cells, cells within organs, organs within individuals, and individuals within both close social groups and large social structures are considered. Furthermore, chapters address the effects of psychological factors on markers of chronic, low-grade, systemic inflammation, which can indicate risk for many disorders including atherosclerosis, Alzheimer's disease, frailty, and some cancers. The volume provides specific applications of psychoneuroimmunological models to fatigue, cancer, neuroinflammation, and pain - and a superb review of the ways psychotherapeutic approaches integrated with psychoneuroimmunological knowledge can mitigate against adverse health outcomes. This volume samples from the best and most sophisticated applications of psychology to PNI, whether those applications arise from affective science, development, behavioral neuroscience, or clinical psychology. Contents: Suzanne C. Segerstrom: Preface
Part One: Development
1. Mary E. Coussons-Read: Stress and Immunity in Pregnancy
2. Christopher L. Coe: The Logic of Developmental Psychoneuroimmunology
3. Elliot M. Friedman: Well-Being, Aging, and Immunity
4. Rita B. Effros: Stress and Immune System Aging
Part Two: Emotion
5. Sally S. Dickerson: Physiological Correlates of Self-Conscious Emotions
6. Sarah D. Pressman and Lora Black: Positive Emotions and Immunity
7. Roger J. Booth: Emotional Expression and Disclosure
Part Three: Personality and Individual Differences
8. Kerry C. Michael and Sonia A. Cavigelli: Temperament/Animal Personality
9. Sheldon Cohen, Denise Janicki-Deverts, Crista N. Crittenden, and Rodlescia S. Sneed: Personality and Human Immunity
10. Edward C. Suarez: The Association Between Measures of Inflammation and Psychological Factors Associated with an Increased Risk of Atherosclerotic Cardiovascular Disease: Hostility, Anger, and Depressed Mood and Symptoms
Part Four: Social Relationships
11. Theodore F. Robles and Heidi S. Kane: Marriage
12. Bert N. Uchino, Allison A. Vaughn, McKenzie Carlisle, and Wendy Birmingham: Social Support and Immunity
13. Andrew Steptoe: Socioeconomic Status, Inflammation, and Immune Function
14. Steven W. Cole: Social Regulation of Gene Expression in the Immune System
Part Five: Ecological Approaches
15. Shelley A. Adamo: Comparative Psychoneuroimmunology/Ecoimmunology: Lessons from Simpler Model Systems
16. Zachary M. Weil and Randy J. Nelson: Seasonal Rhythms in Psychoneuroimmunology
17. Arnaud Aubert: Motivation
Part Six: Clinical Method and Models
18. Shamini Jain, Julienne Bower, and Michael R. Irwin: Psychoneuroimmunology of Fatigue and Sleep Disturbance: The Role of Proinflammatory Cytokines
19. Susan K. Lutgendorf, Erin S. Costanzo, Anil K. Sood: Psychoneuroimmunology and Cancer: Biobehavioral Influences on Tumor Progression
20. Annemieke Kavelaars, Anibal Garza Carbajal, and Cobi J. Heijnen: Regulation of Target System Sensitivity in Neuroinflammation: Role of GRK2 in Chronic Pain
21. Michael H. Antoni: Stress Management, PNI, and Disease
22. Suzanne C. Segerstrom and Gregory T. Smith: Methods, Variance, and Error in Psychoneuroimmunology Research: The Good, the Bad, and the Ugly
Part Seven: Conclusion
23. Suzanne C. Segerstrom: Looking into the Future: Conclusion to The Oxford Handbook of Psychoneuroimmunology About the Editor: Suzanne C. Segerstrom, Ph.D., is Professor of Psychology at the University of Kentucky. Her research focuses on how psychological and behavioral factors such as personality, self-control, and stress affect well-being and health, especially the immune system.
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