This book reviews the recent rapid development of functional neuroimaging techniques and their implications for child psychiatry. It is unique in that it focuses on children and integrates brain mapping with genetics and behavioral testing, an interface that is likely to become fundamental to functional neuroimaging. This invaluable reference will help clinicians and investigators to:
Understand the mechanisms of childhood psychiatric disorders through imaging
Decide the most appropriate technique for their purposes with respect to technology, experimental design, data analysis, and ethical considerations
Appreciate the role of molecular genetics and neuropsychology in planning brain imaging studies. Set against an overview of normal behavioral and cognitive development, the text includes a description of new brain imaging strategies and the application of imaging techniques used on adults to children. Linking the latest findings from neuroimaging to neurophysiological models, this book is an essential resource for researchers and clinicians concerned with neurodevelopmental disorders.
Foreword Joseph Coyle; Preface Monique Ernst and Judith Rumsey; Part I. Techniques of Functional Neuroimaging: 1. Functional brain imaging with PET and SPECT Peter Herscovitch and Monique Ernst; 2. Modeling of PET/SPECT receptor images Evan Morris, Raymond Muzic, Bradley Christian, Christopher Endres and Ronald Fisher; 3. Techniques of functional neuroimaging: functional magnetic resonance imaging (fMRI) Guinevere F. Eden and Thomas A. Zeffiro; 4. MRS in childhood psychiatric disorders Deborah Yurgelun-Todd and Perry Renshaw; 5. Magnetoencephalography (MEG) Donald Rojas, Peter Teale and Martin Reite; Part II. Ethical Issues in Neuroimaging Reseach with Children Eugene Arnold, Alan Zametkin, Lauren Caravella and Nicole Korbly; Part III. Normal Development: 6. Brain development and evolution Manuel Casanova, Daniel Buxhoeveden and Gurkirpal Sohal; 7. Cognitive development from a neuropsychological perspective Daisy Pascualvaca and Gloria Morote; 8. Cognitive and behavioural probes of developmental landmarks for use in functional neuroimaging B. J. Casey, Kathleen Thomas, Tomihisa Welsh, Rona Livnat and Clayton Eccard; Part IV. Psychiatric Disorders: 9. Autism Diane Chugani; 10. Functional imaging in childhood onset schizophrenia Leslie Jacobsen and Alessandro Bertolino; 11. Pediatric mood disorders and neuroimaging Robert A. Kowatch, Pablo Davanzo and Graham J. Emslie; 12. New frontiers in neuroimaging of childhood onset anxiety disorders David Rosenberg, Lori Paulson, Frank MacMaster and Gregory Moore; 13. Functional brain imaging in Tourette's syndrome: what are we really imaging? Bradley Peterson and Prakash Thomas; 14. Functional neuroimaging in dyslexia: conceptual issues and psychiatric comorbidity Frank Wood and Lynn Flowers; 15. Attention deficit hyperactivity disorder: neuroimaging and behavioural/cognitive probes Julie B. Schweitzer, Carl Anderson and Monique Ernst; 16. Eating disorders Uttom Chowdhury, Isky Gordon and Bryan Lask; Part V. Future Directions: 17. Techniques of molecular genetics David Vandenbergh; 18. Issues in the genetic study of complex neurobehavioral conditions David Pauls; 19. The duplicity of plasticity: a conceptual approach to the study of early lesions and developmental disorders Ralph Axel Mueller and Eric Courchesne; 20. Utility of the CANTAB battery in functional neuroimaging A. C. H. Lee, A. M. Owen, R. D. Rogers, B. J. Sahakian and T. W. Robbins; 21. Neurodevelopmental assessment of cognitive function using the Cambridge Neuropsychological Testing Automated Battery (CANTAB): validation and future goals Monica Luciana and Charles Nelson; 22. Functional neuroimaging in child psychiatry: future directions Monique Ernst and Judith Rumsey; Glossary; Index.
"...a comprehensive overview of the main issues in developmental functional neuroimaging...an interesting, informative and comprehensive textbook on the subject; worthwhile reading for the lay reader, the novice and the expert." Katya Rubia, Institute of Psychiatry, King's College, London, Cognitive Neuropsychiatry
"This large and very attractive volume lays out a blueprint for the future of child psychiatry." Journal of Clinical Psychiatry
"This book will be of great use to doctors, researchers and teachers... This very clear, current and rigorous work brings psychiatry and neurology to its origins." European Journal of Psychiatry
Joseph Coyle, Monique Ernst, Judith Rumsey, Peter Herscovitch, Evan Morris, Raymond Muzic, Bradley Christian, Christopher Endres, Ronald Fisher, Guinevere F. Eden, Thomas A. Zeffiro, Deborah Yurgelun-Todd, Perry Renshaw, Donald Rojas, Peter Teale, Martin Reite, Eugene Arnold, Alan Zametkin, Lauren Caravella, Nicole Korbly, Manuel Casanova, Daniel Buxhoeveden, Gurkirpal Sohal, Daisy Pascualvaca, Gloria Morote, B. J. Casey, Kathleen Thomas, Tomihisa Welsh, Rona Livnat, Clayton Eccard, Diane Chugani, Leslie Jacobsen, Alessandro Bertolino, Robert A. Kowatch, Pablo Davanzo, Graham J. Emslie, David Rosenberg, Lori Paulson, Frank MacMaster, Gregory Moore, Bradley Peterson, Prakash Thomas, Frank Wood, Lynn Flowers, Julie B. Schweitzer, Carl Anderson, Monique Ernst, Uttom Chowdhury, Isky Gordon, Bryan Lask, David Vandenbergh, David Pauls, Ralph Axel Mueller, Eric Courchesne, A. C. H. Lee, A. M. Owen, R. D. Rogers, B. J. Sahakian, T. W. Robbins, Monica Luciana, Charles Nelson