Edited by the president of the World Federation of Societies of Biological Psychiatry and featuring an international list of world-renown contributors, Schizophrenia, Second Edition provides psychiatrists, neurologists, and psychologists with a comprehensive handbook on the latest schizophrenia research and management from diagnosis through treatment. New features in this user-friendly Second Edition: • Two-thirds new content, including 20 chapter additions detailed coverage of interviewing, symptomatology evaluation, and cognitive assessment strategies to ensure accurate differential diagnosis • An in-depth discussion of both pharmacological and nonpharmacological treatment options • A section on the neurobiology of schizophrenia, covering the latest in genetic and epigenetic factors, brain abnormalities, neuroimaging, biochemical alterations, and social cognition • Treatment options for management of the disease, including treatment of the first schizophrenic episode, pharmacogenetic approaches, comparative efficacy of older vs. new antipsychotic medication, managing side-effects, psychosocial and cognitive rehabilitation, psychotherapy, and rehabilitation strategies Table of Contents Diagnosis and Psychopathology Schizophrenia: Historical roots and brief review of recent research developments Costas N Stefanis and Nick C Stefanis Epidemiology and gender Johannes Wancata, Marion Freidl, and Annemarie Unger Interviewing the patient with schizophrenia Florence Thibaut Evaluation of symptomatology on schizophrenia Julio Bobes, Maria P Garcia-Portilla, Pilar A Saiz, and Manuel Bousoño Clinical characteristics of first-episode schizophrenia Lisa P Henry, Patrick D McGorry, Meredith G Harris, and Paul Amminger Schizophrenia: Differential diagnosis and comorbidities Carlo A Altamura, Filippo Dragogna, Sara Pozzoli, and Massimo C Mauri Neurocognition and schizophrenia Gabriele Sachs Neurobiology Genetic and epigenetic factors in schizophrenia Alexandra Schosser and Peter McGuffin Brain abnormalities in schizophrenia Bernhard Bogerts, Johann Steiner and Hans-Gert Bernstein Imaging in schizophrenia Wiepke Cahn, Neeltje EM van Haren, and Rene S Kahn Biochemical alterations in schizophrenia Birte Yding Glenthoj, Lars V Kristiansen, Hans Rasmussen, and Bob Oranje Dopamine dysregulation in the brain network of decision-making: Can this explain the psychopathology of schizophrenia? Seyed M Assadi, Murat Yücel, and Christos Pantelis Neuropsychological markers and social cognition in schizophrenia Jonathan Burns Pharmacological Treatment Strategies An update of meta-analyses on second-generation antipsychotic drugs for schizophrenia Stefan Leucht, Caroline Corves, Werner Kissling, and John M Davis Maintenance pharmacotherapy in schizophrenia Siegfried Kasper, Elena Akimova, Martin Fink, and Rupert Lanzenberger Evaluation and medication therapy for treatment resistance in schizophrenia Robert R Conley First episode schizophrenia: Considerations on the timing, selection, and duration of antipsychotic therapies Brian J Miller and Peter F Buckley Pharmacological profile and pharmacogenetic approaches of antipsychotics Min-Soo Lee and Hun Soo Chang Side effect burden of antipsychotic medication Hans-Jürgen Möller and Michael Riedel Nonpharmacological Treatment Rehabilitation in schizophrenia: Social skills training and cognitive remediation Joseph Ventura and Lisa H Guzik Evidence-based psychosocial interventions for schizophrenia Eric Granholm and Catherine Loh Transcultural psychiatry and schizophrenia Thomas Stompe Electroconvulsive therapy in schizophrenia Georgios Petrides and Raphael J Braga Schizophrenia and Society Schizophrenia and stigma: Old problems, new challenges Marina P Economou, Nick C Stefanis, and George N Papadimitriou Patient rights: Ethics and the clinical care of patients with schizophrenia Evan G DeRenzo, Steve Peterson, Jack Schwartz Alexis Jeannotte, and Steve Selinger Genetic counseling in schizophrenia Dimitris G Dikeos, Evangelos Vassos, and George N Papadimitriou Violence in schizophrenia: Risk factors and assessment John Rabun and Susan Boyer Economic evaluation and schizophrenia Martin Knapp and Denise Razzouk Transcultural aspects of schizophrenia and old-age schizophrenia Tarek Okasha and Ahmed Okasha |