Key Features Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible Description The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Readership Researchers, clinicians, and students in neuroscience, neurology, psychiatry and psychology CONTENTS The Neurobiology of Schizophrenia, 1st Edition Clinical and Historical Overview Genetic and Epigenetic Basis of Schizophrenia Neurochemical Basis of Schizophrenia Biochemical Basis of Schizophrenia Structural basis of Schizophrenia Electrophysiological Basis of Schizophrenia Function of Neural Circuits in Schizophrenia Modeling Schizophrenia in Animals Future Perspectives of Schizophrenia Research About the Editors Dr. Ted Abel is the Brush Family Professor of Biology in the School of Arts and Sciences at the University of Pennsylvania. Dr. Abel is also Co-Director of the Biological Basis of Behavior Program and he directs an NIMH-funded predoctoral training program in behavioral and cognitive neuroscience. He is Editor-in-Chief of Neurobiology of Learning and Memory. Affiliations and Expertise University of Pennsylvania, Philadelphia, PA, USA Dr. Nickl-Jockschat is a Professor and Doctor of Psychiatry and Psychotherapy at RWTH Aachen University Hospital. He specializes in Schizophrenia, Autism, and synaptic plasticity. He is a Reviews Editor for Frontiers in Neuropsychiatric Imaging and Stimulation. Affiliations and Expertise RWTH Aachen University Hospital, Aachen, Germany Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance, this text offers a comprehensive overview of the neurobiological aspects of schizophrenia by examining the disorder at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels |