Drug Metabolism in Psychiatry: A Clinical Guide bridges the gap between the complexities of drug pharmacokinetics and everyday clinical practice. In straightforward language, Dr. Carlat teaches the basics of drug metabolism, providing clinicians more insight into how psychiatric drugs behave (or misbehave!) once their patients take them. The book also includes a series of unusually practical drug interactions charts that prescribers will find invaluable as they make medication decisions.
"Not only useful, but engaging and entertaining." -S. Nassir Ghaemi, MD, MPH "Dr. Carlat is a master at making tedious concepts come to life--I wish I had this book when I started my residency!" Claudia Baldassano, MD Assistant Professor of Clinical Psychiatry, University of Pennsylvania, School of Medicine, Director, Bipolar Outpatient Program
"A complete and informative, yet clever and entertaining exploration of a vitally important domain of psychiatry. This work is a must for the busy psychiatrist who has meant to learn more about drug metabolism, but never had the time. I highly recommend it." -Neil Sandson, MD Director of Residency Training, Sheppard Pratt Health System Author, Drug-Drug Interaction Primer: A Compendium of Case Vignettes for the Practicing Clinician
Table of Contents:
Acknowledgments Preface Preface to Third Edition I. The Basics 1. Introduction: An Overview of Drug Metabolism 2. What Happens After You Swallow a Pill: Absorption 3. Half-Life, Onset, Duration: Some Concepts to Help You Prescribe 4. Tweaking Pills: How Extended-Release Medications Work 5. Now, Get Rid of It: Biotransformation 6. Cutting to the Chase: Clinically Relevant Drug-Drug Interactions in Psychiatry II. Special Topics 7. Prescribing for the Elderly and the Young 8. Pharmacodynamic Drug Interactions 9. Generic Medications and Drug Metabolism 10. The Kidney and Psychiatric Medications 11. Pharmacogenetic Testing: Is it Useful in Your Practice? Appendix Tables and Charts Half-Lives of Psychiatric Medications Psychiatric Drug Interactions by Medication Psychiatric Drug Interactions by Enzyme Family Common Non-Psychiatric Meds and Their Interactions Annotated (and Opinionated) Bibliography Index
About the Author:
Daniel J. Carlat, MD, editor-in-chief of The Carlat Psychiatry Report, is associate clinical professor of psychiatry at Tufts University, and is the author of The Psychiatric Interview (Lippincott Williams & Wilkins), now in its third edition.