Recent advances in evidence-based treatment of pediatric bipolar disorder are comprehensively reviewed in this authoritative volume. The prominent editors and contributors examine the current status of widely used medications and psychosocial therapies, as well as exploring new horizons in tailoring treatment to individuals' neurobiological and clinical profiles. Chapters on specific populations discuss strategies for addressing common co-occurring disorders in children and adolescents with bipolar disorder, treating preschoolers, targeting bipolar depression, and improving early intervention and prevention. Other essential topics include medication side effects and approaches to monitoring and ameliorating them, and ethical issues related to treatment and research. Reviews: "This exemplary book, full of rich, age-specific treatment information, is an amazing reflection of the growth in knowledge on treatment of children and adolescents with bipolar disorder. The editors are to be commended for the quality of the individual chapters, which are written by clinician-researchers who are the leaders in their respective areas and who present a very balanced view of the treatment of this complex disorder. The book highlights exciting advances in such areas as matching treatment to individuals and integrating psychopharmacological and psychosocial interventions. An invaluable resource for clinicians and researchers."--Graham Emslie, MD, Charles E. Seay and Sarah M. Seay Chair in Child Psychiatry, University of Texas Southwestern Medical Center at Dallas "This timely book reflects a range of recent developments in the field. Unique features include the discussions of metabolic considerations; recent advances in pharmacological treatments; and chapters on preschool presentation, early intervention, and ethics that present important perspectives on complex issues. Readers will be pleasantly impressed with the progress and consensus charted in this book."--Eric Youngstrom, PhD, Departments of Psychology and Psychiatry, and Associate Director, Center of Excellence for Research and Treatment of Bipolar Disorder, University of North Carolina at Chapel Hill Contents: 1. Introduction, Melissa P. DelBello and Barbara Geller I. Diagnosis and Treatments 2. Diagnosis, Prognosis, and Personalized Medicine, Rebecca Tillman and Barbara Geller 3. Neuropsychopharmacology, Nick C. Patel and Melissa P. DelBello 4. Lithium, Robert L. Findling and Mani N. Pavuluri 5. Atypical Antipsychotics in the Treatment of Early-Onset Bipolar Disorder, Jean A. Frazier, Hallie Bregman, and Joseph A. Jackson 6. Mood Stabilizers, Robert A. Kowatch 7. Newer Drugs, Adelaide S. Robb and Paramjit T. Joshi 8. Nonpharmacological Biological Treatment for Pediatric Bipolar Disorder: Omega-3 Fatty Acids and Complementary and Alternative Medicine Russell E. Scheffer 9. Family-Focused Treatment for Bipolar Disorder in Adolescence, David J. Miklowitz, Kimberley L. Mullen, and Kiki D. Chang 10. Psychoeducational Psychotherapy, Kristen H. Davidson and Mary A. Fristad II. Comorbid Disorders and Special Populations 11. Pharmacotherapy for Attention-Deficit/Hyperactivity Disorder in Children with Mania, Karen Dineen Wagner 12. Pediatric Bipolar Disorder and Substance Use Disorders: The Nature of the Relationship, Subtypes at Risk, and Treatment Issues, Timothy E. Wilens and Martin Gignac 13. Pediatric Bipolar Disorder and Comorbid Conditions: Treatment Implications, Gagan Joshi and Janet Wozniak 14. Treatment of Preschool Bipolar Disorder: A Novel Parent–Child Interaction Therapy and Review of Data on Psychopharmacology, Joan L. Luby, Melissa Meade Stalets, Samantha Blankenship, Jennifer Pautsch, and Molly McGrath 15. Treatment of Children and Adolescents at High Risk for Bipolar Disorder, Kiki D. Chang 16. Treatment of Bipolar Depression, Shannon Rae Barnett, Mark A. Riddle, and John T. Walkup III. Other Issues 17. Polycystic Ovary Syndrome, Paramjit T. Joshi and Adelaide S. Robb 18. Weight Gain and Metabolic Abnormalities in Pediatric Bipolar Disorder, Christoph U. Correll 19. Ethical and Regulatory Aspects in the Treatment of Children and Adolescents with Bipolar Disorder, Benedetto Vitiello Contributors: Shannon Rae Barnett, MD, is Assistant Professor of Psychiatry in the Division of Child and Adolescent Psychiatry at the Johns Hopkins University School of Medicine, Baltimore, Maryland. Samantha Blankenship, MSW, is the study monitor for the Treatment of Early Age Mania Study at Washington University School of Medicine in St. Louis, St. Louis, Missouri. Hallie Bregman, BA, is a research coordinator at the Child and Adolescent Neuropsychiatric Research Program at Cambridge Health Alliance, Cambridge, Massachusetts. Kiki D. Chang, MD, is Associate Professor of Psychiatry and Behavioral Sciences at the Stanford University School of Medicine, Division of Child Psychiatry, Stanford, California. Christoph U. Correll, MD, is Assistant Professor of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York. Kristen H. Davidson, PhD, is in private practice in Rochester, New York, and is a clinical senior instructor in the Departments of Psychiatry and Pediatrics at the University of Rochester Medical Center, Rochester, New York. Melissa P. DelBello, MD, MS, is Associate Professor of Psychiatry and Pediatrics, Vice-Chair for Clinical Research, and Codirector, Division of Bipolar Disorders Research at the University of Cincinnati College of Medicine, and Director, Research Education and Training, Child and Adolescent Psychiatry Division, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio. Robert L. Findling, MD, is Director of the Division of Child and Adolescent Psychiatry at University Hospitals Case Medical Center and Professor of Psychiatry and Pediatrics at Case Western Reserve University, Cleveland, Ohio. Jean A. Frazier, MD, is Director of Child Psychopharmacology and the Child and Adolescent Neuropsychiatric Research Program at Cambridge Health Alliance, Cambridge, Massachusetts, where she is also Codirector of the Center for Child and Adolescent Development, and is Associate Professor of Psychiatry at Harvard Medical School, Boston, Massachusetts. Mary A. Fristad, PhD, is Professor of Psychiatry and Psychology at The Ohio State University (OSU), and Director of Research and Psychological Services in the OSU Division of Child and Adolescent Psychiatry, Columbus, Ohio. Barbara Geller, MD, is Professor of Psychiatry at Washington University School of Medicine in St. Louis. Martin Gignac, MD, FRCP, is a psychiatrist and clinical research coordinator at the adolescents’ unit of the Institut Philippe-Pinel de Montréal, Montréal, Québec, Canada. Joseph A. Jackson, DO, is Instructor in Psychiatry at Harvard Medical School and is Medical Director of the Developmental Disabilities Program at the Center for Child and Adolescent Development, Cambridge Health Alliance, Cambridge, Massachusetts. Gagan Joshi, MD, is Scientific Director of the Pervasive Developmental Disorders Research Program in the Pediatric Psychopharmacology Unit at the Massachusetts General Hospital, and Instructor in Psychiatry at Harvard Medical School, Boston, Massachusetts. Paramjit T. Joshi, MD, is Endowed Chair of the Department of Psychiatry and Behavioral Sciences at the Children’s National Medical Center, and Professor of Psychiatry, Behavioral Sciences and Pediatrics at the George Washington University School of Medicine, Washington, DC. Robert A. Kowatch, MD, is Professor of Psychiatry and Pediatrics at Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio. Joan L. Luby, MD, is Associate Professor of Child Psychiatry and founder and director of the Early Emotional Development Program at the Washington University School of Medicine in St. Louis, St. Louis, Missouri. Molly McGrath, LCSW, is a research clinician with the Early Emotional Development Program at Washington University School of Medicine in St. Louis, St. Louis, Missouri. David J. Miklowitz, PhD, is Professor of Psychology and Psychiatry at the University of Colorado, Boulder, Colorado, and a senior clinical Research Fellow in the Department of Psychiatry at Oxford University, Oxford, United Kingdom. Kimberley L. Mullen, MA, is a doctoral candidate in clinical psychology at the University of Colorado, Boulder, Colorado. Nick C. Patel, PharmD, PhD, is Assistant Professor of Pharmacy at the University of Georgia, Athens, Georgia, and Assistant Professor of Psychiatry at the Medical College of Georgia, Augusta, Georgia. Jennifer Pautsch, MA, is a study coordinator for the Early Intervention in Depression Study and oversees the clinical research mental health assessments in the Early Emotional Development Program at Washington University School of Medicine in St. Louis, St. Louis, Missouri. Mani N. Pavuluri, MD, PhD, is Associate Professor of Psychiatry and Director of the Pediatric Mood Disorders Program at the University of Illinois at Chicago, Chicago, Illinois. Mark A. Riddle, MD, is Professor of Psychiatry and Pediatrics and Director of the Division of Child and Adolescent Psychiatry at the Johns Hopkins University School of Medicine, Baltimore, Maryland. He also serves as Vice President for Psychiatric Sciences at the Kennedy Krieger Institute. Adelaide S. Robb, MD, is Associate Professor of Psychiatry and Pediatrics at the Children’s National Medical Center, Washington, DC, where she is Medical Director of Inpatient Psychiatry. Russell E. Scheffer, MD, is Professor and Chair of the Department of Psychiatry and Behavioral Sciences and Professor of Pediatrics at the Kansas University Medical Center–Wichita, Wichita, Kansas. Melissa Meade Stalets, MA, is an infant mental health specialist for an early intervention program in Illinois, and formerly was a researcher in the Early Emotional Development Program at the Washington University School of Medicine in St. Louis, St. Louis, Missouri. Rebecca Tillman, MS, is a senior statistical data analyst at Washington University School of Medicine in St. Louis, St. Louis, Missouri. Benedetto Vitiello, MD, is Chief of the Child and Adolescent Treatment and Preventive Interventions Research Branch, National Institute of Mental Health, and is Adjunct Professor of Psychiatry at Johns Hopkins University, Baltimore, Maryland. Karen Dineen Wagner, MD, PhD, is the Marie B. Gale Professor and Vice Chair in the Department of Psychiatry and Behavioral Sciences and Director of the Division of Child and Adolescent Psychiatry at the University of Texas Medical Branch in Galveston, Texas. John T. Walkup, MD, is Associate Professor of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Johns Hopkins Medical Institutions in Baltimore, Maryland, where he currently serves as Deputy Director of the Division of Child and Adolescent Psychiatry. Timothy E. Wilens, MD, is Associate Professor of Psychiatry at Harvard Medical School, Boston, Massachusetts, and is Director of Substance Abuse Services in the Clinical and Research Program in Pediatric Psychopharmacology at Massachusetts General Hospital. Janet Wozniak, MD, is Director of the Pediatric Bipolar Disorder Research Program in the Pediatric Psychopharmacology Unit at the Massachusetts General Hospital, and Assistant Professor of Psychiatry at Harvard Medical School, Boston, Massachusetts.
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